Bo Xia
Welcome!
Hi, welcome to my personal space! I am a Junior Fellow of the Society of Fellows at Harvard University. I am also Gene Regulation Observatory Fellow and a Principal Investigator at the Broad Institute of MIT and Harvard. I recently received my Ph.D. degree from NYU School of Medicine, co-mentored by Dr. Itai Yanai and Dr. Jef D. Boeke. Working with two great mentors with complementary backgrounds allows me to think about the genome in a broader view. I’m combining both experimental approaches and computational tools to understand the principles and mechanisms in genome regulation across development, disease, and evolution. You will find more about me through my science and stories.
NEWS
November 01, 2020
NYSTEM Pre-doctoral Training Fellowship
I'm excited to receive a one-year NYSTEM Pre-doctoral Training Fellowship ($30,000) to support my PhD research in the Yanai and Boeke labs. Looking forward to sharing our discoveries soon.
June 22, 2020
Winner of the 2020 Regeneron Prize for Creative Innovation
I feel extremely honored and grateful for sharing the 2020 Regeneron Prize for Creative Innovation. It was a fun and fulfilling journey, especially during this difficult time. Science and Innovations can be – and should be – the solution to many problems we are facing right now.
March 08, 2020
Coming back from the SALT2020 program at NYAS
Coming back from the 5-day Science Alliance Leadership Training (SALT) 2020 program at NYAS! Learned and grew so much in such an intense while empowering program! THE one thing I learned about myself/team: clearly define the goal! You may think it’s obvious, but not seem so in the real world.
January 23, 2020
Transcriptional Scanning paper published on Cell!
Our 'transcriptional scanning' paper is formally published on Cell, as a cover story! We addressed the long-standing mystery that testis has the most widespread transcriptome, and proposed that ‘transcriptional scanning’ modulates gene mutation rates, and ultimately gene evolution rates! Along with the article is a Preview led by Dr. Bluma J. Lesch. Sperm Go to (Transcription) Extremes. Check it out! Link
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RESEARCH INTERESTS
Single-cell and spatial transcriptomics
Nature built a Lego castle, and we are dismantling it to understand how it was built.
Genome evolution
Mutations are roughly random, but evolution is not.
Epigenetics and chemical biology
Sometimes a small chemistry makes a big difference in biology.